Click here to view datasheet

Rabbit Monoclonal Antibody

Description: PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.

Clone Designation: EP1588Y

Immunogen: A synthetic peptide corresponding to residues near the C-term. of human PSA.

Positive Control:Normal prostate or prostate carcinoma

Molecular Weight:34kDa

Species reactivity:Human. Others-not known

Cellular Localization:Cytoplasmic