Lab Vision Corporation, a part of Thermo Fisher Scientific

GCDFP-15 (Gross Cystic Disease Fluid Protein-15) Ab-1

Mouse Monoclonal Antibody

Description: Gross cystic disease of the breast is benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is composed of several glycoproteins including a unique 15kDa monomer protein, Gross Cystic Disease Fluid Protein-15 (GCDFP15). Cytosolic analysis of normal tissue specimens from all major organs has demonstrated GCDFP15 in apocrine epithelia, lacrimal, ceruminous and Moll’s glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. GCDFP15 and prostate specific antigen are co-expressed in androgen receptor-positive breast tumours.

Comments: Ab-1 may be of use in the identification of breast carcinoma, salivary duct carcinoma and apocrine epithelia.

Clone Designation: 23A3

Immunogen: Recombinant protein encoding the excreted domain of human GCDFP15.

Positive Control:Skin

Molecular Weight:15kDa

Species reactivity:Human and Rat. Others not-known.

Cellular Localization:Cytoplasmic

Please select from the items below to add to your shopping cart:

	Cat. # MS-1170 - R7
	( 7.0ml ) ( Ready-to-use for Immunohistochemical Staining)
	Cat. # MS-1170 - PCS
	( Positive Control for Histology, a set of 5 slides)
	Cat. # MS-1170 - S1
	( 0.5ml ) ( Supernatant)
	Cat. # MS-1170 - S0
	( 0.1ml ) ( Supernatant)
	Cat. # MS-1170 - S
	( 1.0ml ) ( Supernatant)

Formalin-fixed, paraffin-embedded human skin stained with NeoMarkers' GCDFP15 Ab-1 (Cat. #MS-1170-S) using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of epithelial cells in the sweat glands.