Lab Vision Corporation, a part of Thermo Fisher Scientific

AbName	Catalog number	Clone	Applications	Immunogen	Epitope	Species Reactivity	Comments
Keratin, Pan Ab-1	MS-343	AE1/AE3	Immunohistology (Formalin/paraffin), Immunofluorescence	Human epidermal keratin	-	Human, Monkey, Cow, Rabbit, Mouse, Rat, Chicken. Others-not known.	MAb AE1 recognizes the 56.5, 50, 50’, 48, and 40kDa keratins of acidic subfamily, whereas the AE3 MAb reacts with the basic keratins of 65-67, 64, 59, 58, 56, and 52kDa. AE1/AE3 reacts with keratinized (56.5/65-67) and corneal (55/64) epidermis, stratified squamous epithelia of internal organs (51/59), stratified epithelia (50/58), hyperproliferative keratinocytes (48/56), and simple epithelia (45/52 and 46/54). AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail which differentiates epithelial from non-epithelial tumors.
Keratin, Pan Ab-2	MS-356	PAN-CK	Immunofluorescence, Immunohistology (Formalin/paraffin)	-	Not determined	Human. Others not known.	Ab-2 is a broad spectrum anti pan-keratin antibody cocktail, which recognizes keratins 4, 5, 6, 7, 8, 10, 13, 14, 15, 16, 18, and 19. . Ab-2 cocktail differentiates epithelial tumors from non-epithelial tumors.
Keratin, Pan Ab-3	MS-744	Lu-5	Immunohistology (Formalin/paraffin), Immunofluorescence	Lung cancer cell line	Not determined	Human, Cow, Rat, Chicken, Snake, and Frog. Shows a very wide reactivity in vertebrates.	Ab-3 recognizes the keratins of acidic as well as basic subfamilies. It reacts with keratinized and corneal epidermis, stratified squamous epithelia of internal organs, stratified epithelia, hyperproliferative keratinocytes, and simple epithelia. Ab-3 is a broad spectrum anti pan-keratin antibody, which differentiates epithelial from non-epithelial tumors. Unlike AE1/AE3 pan-keratin antibody, Lu-5 works well with pepsin digestion of formalin-fixed tissues.