Melanoma Marker, Pan Ab-1

Antibodies

Melanoma Marker, Pan Ab-1

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Compare different antibodies against Melanoma Marker.

Mouse Monoclonal Antibody

Description: Melanoma associated antigens recognized by autologous cytotoxic T cells include MART-1, MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.

Comments: Ab-1 is a cocktail of anti-gp100 (HMB45) and MART-1 antibodies. By immunohistochemistry, Ab-1 recognizes melanocytes and melanomas. This MAb cocktail reacts with junctional and blue nevus cells and with fetal and neonatal melanocytes. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Ab-1 labels melanotic as well as amelanotic variants of melanomas. Ab-1 is extremely sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

IgIsotype: IgG1 / kappa+ IgG2b / kappa +IgG2b / kappa

Clone Designation: HMB45 (gp100, M2-7C10 (MART-1 and M2-9E3 (MART-1)

Immunogen: Extract of pigmented melanoma metastases from lymph nodes (HMB45); Recombinant hMART-1 protein (M2-7C10 and M2-9E3).

Positive Control:Melanoma

Cellular Localization:Cytoplasmic

Molecular Weight:100kDa (gp100) and 18kDa (MART-1)

Species reactivity:Human and Horse. Others-not known.

Please select from the items below to add to your shopping cart:

	Cat. # MS-939 - S1
	( 0.5ml ) ( Supernatant)
	Cat. # MS-939 - S0
	( 0.1ml ) ( Supernatant)
	Cat. # MS-939 - S
	( 1.0ml ) ( Supernatant)
	Cat. # MS-939 - PCS
	( Positive Control for Histology, a set of 5 slides)
	Cat. # MS-939 - R7
	( 7.0ml ) ( Ready-to-use for Immunohistochemical Staining)

Formalin-fixed, paraffin-embedded human melanoma stained with NeoMarkers' Melanoma, Pan Ab-1 (Cat. #MS-939-S) using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.