Rabbit Monoclonal Antibodies

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Antibodies

 

MART-1 / Melan-A (Melanoma Marker) Ab-3 (Cocktail)

Click here to view datasheet for research use Click here to view RUO datasheet

Click here to view PCL datasheet Click here to view PCL datasheet

Compare different antibodies against MART-1.Click here to compare differnt antibodies

Mouse Monoclonal Antibody

Description: MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-Ais a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.

Comments: Ab-3 is a cocktail of Ab-1 and Ab-2. Ab-3 labels melanomas and other tumors showing melanocytic differentiation. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Ab-3 is particularly designed for sensitive detection of MART-1/melan A protein.

IgIsotype: IgG2b / kappa + IgG2b / kappa

Epitope: Not determined

Clone Designation: M2-7C10 + M2-9E3

Immunogen: Recombinant hMART-1 protein.

Positive Control:CAC1 melanoma cells and Melanomas.

Cellular Localization:Cytoplasmic

Molecular Weight:18kDa

Species reactivity:Human and Horse. Others-not known.





Please select from the items below to add to your shopping cart:

Cat. # MS-716 - P0
  ( 0.1ml at 200ug/ml)
( Purified Ab with BSA and Azide)

Cat. # MS-716 - P1ABX
  ( 0.1ml at 1.0mg/ml)
( Purified Ab without BSA and Azide)

Cat. # MS-716 - PABX
  ( 0.2ml at 1.0mg/ml)
( Purified Ab without BSA and Azide)

Cat. # MS-716 - R7
  ( 7.0ml )
( Ready-to-use for Immunohistochemical Staining)

Cat. # MS-716 - PCS
  ( Positive Control for Histology, a set of 5 slides)

Cat. # MS-716 - PCL
  ( 0.1ml at 250ug/0.1ml)
( Positive Control for Western Blot)

Cat. # MS-716 - P1
  ( 0.5ml at 200ug/ml)
( Purified Ab with BSA and Azide)

Cat. # MS-716 - P
  ( 1.0ml at 200ug/ml)
( Purified Ab with BSA and Azide)


  
Formalin-fixed, paraffin-embedded human compound nevus stained with NeoMarkers
Formalin-fixed, paraffin-embedded human compound nevus stained with NeoMarkers' MART-1 Ab-3 (Cat. #MS-716-P) using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of melanocytes.



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