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RPA / p70 (Replication Protein A) Ab-2
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Compare different antibodies against RPA / p70.
Mouse Monoclonal Antibody
Description: Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA70 is composed of three domains: an N-terminal domain that is not required for ssDNA binding or SV40 replication, a central DNA-binding domain, and a C-terminal domain that is essential for subunit interactions.
IgIsotype: IgG1 / kappa
Epitope: Not determined
Clone Designation: 2H10 or 70C or alphaSSB70C
Immunogen: Purified human RPA protein.
Positive Control:HeLa cells.
Cellular Localization:Nuclear
Molecular Weight:70kDa
Species reactivity:Human. Others not known.
  
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