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ROC1 Ab-1
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Compare different antibodies against ROC1.
Rabbit Polyclonal Antibody
Description: ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.
IgIsotype: IgG
Epitope: aa 97-108
Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1.
Positive Control:HeLa cells.
Cellular Localization:Nuclear
Molecular Weight:13kDa
Species reactivity:Human and Mouse. Others-not known.
  
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