XPA Ab-1

Antibodies

XPA Ab-1

Click here to view datasheet for research use

Click here to view PCL datasheet

Compare different antibodies against XPA.

Mouse Monoclonal Antibody

Description: The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-or chemically damaged DNA lesions, and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or the excision repair cross complementing 1 protein (ERCC1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a > 2000 fold increased risk to develop skin cancer at sun-exposed areas.

IgIsotype: IgG2a / kappa

Epitope: Not determined

Clone Designation: 12F5

Immunogen: Recombinant human XPA protein.

Positive Control:LS174T or MCF-7 cells or human tonsil.

Cellular Localization:Nuclear

Molecular Weight:~40kDa

Species reactivity:Human. Others-not known.

Please select from the items below to add to your shopping cart:

	Cat. # MS-650 - P1
	( 0.5ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-650 - PCL
	( 0.1ml at 250ug/0.1ml) ( Positive Control for Western Blot)
	Cat. # MS-650 - PCS
	( Positive Control for Histology, a set of 5 slides)
	Cat. # MS-650 - R7
	( 7.0ml ) ( Ready-to-use for Immunohistochemical Staining)
	Cat. # MS-650 - PABX
	( 0.2ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-650 - P
	( 1.0ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-650 - P0
	( 0.1ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-650 - P1ABX
	( 0.1ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)

Formalin-fixed, paraffin-embedded human tonsil stained with NeoMarkers’ XPA Ab-1 (Cat. #MS-650-P) using peroxidase-conjugate and AEC chromogen. Note nuclear staining of epithelial cells.