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Adenovirus Type 2 E1A Ab-2
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Compare different antibodies against Adenovirus.
Mouse Monoclonal Antibody
Description: The adenovirus early gene product E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth-inhibitory effects of TGF-beta. The E1A region encodes a series of related proteins (35-46kDa) with multifuctional capabilities and form a specific complex with the retinoblastoma tumor suppressor gene product (Rb protein). The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region.
Comments: Ab-2 immunoprecipitates E1A associated proteins.
IgIsotype: IgG2a / kappa
Clone Designation: M73
Immunogen: Adenovirus.
Positive Control:293 cells or adenovirus infected tissues.
Cellular Localization:Nuclear
Molecular Weight:35-46kDa
Species reactivity:Adenovirus.
  
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