Ku (p70 / p80) Ab-3

Antibodies

Ku (p70 / p80) Ab-3

Click here to view datasheet for research use

Compare different antibodies against Ku.

Mouse Monoclonal Antibody

Description: The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

IgIsotype: IgG2a

Epitope: A conformational epitope of p70/p80 dimer, which is destroyed during Western blotting

Clone Designation: 162

Immunogen: Human B cell nuclei from plasmacytoid 2p68 cells

Positive Control:Tonsil.

Cellular Localization:Nuclear

Molecular Weight:70kDa and 80kDa

Species reactivity:Human, Monkey, Xenopus. Mouse and Rat (Immunoprecipitation only). Does not react with cow and rabbit.

Please select from the items below to add to your shopping cart:

	Cat. # MS-286 - P
	( 1.0ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-286 - PABX
	( 0.2ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-286 - P1ABX
	( 0.1ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-286 - R7
	( 7.0ml ) ( Ready-to-use for Immunohistochemical Staining)
	Cat. # MS-286 - P1
	( 0.5ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-286 - PCS
	( Positive Control for Histology, a set of 5 slides)
	Cat. # MS-286 - P0
	( 0.1ml at 200ug/ml) ( Purified Ab with BSA and Azide)

Formalin-fixed, paraffin-embedded human tonsil stained with NeoMarkers' Ku Ab-3 (Cat. #MS-286-P) using peroxidase-conjugate and AEC chromogen. Note nuclear staining of the cells.