Plastin-L Ab-1

Antibodies

Plastin-L Ab-1

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Compare different antibodies against Plastin-L.

Mouse Monoclonal Antibody

Description: L-plastin. It is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosteronse in andrgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.

Comments: Ab-1 does not react with T- or I-plastin.

IgIsotype: IgG1

Epitope: Headpiece region

Clone Designation: LPL4A.1

Immunogen: Human recombinant L-plastin protein.

Positive Control:Human polymorphonuclear neutrophils and monocytes, MCF-7, Jurkat cells.

Cellular Localization:Cytoplasmic

Molecular Weight:62kDa

Species reactivity:Human. Does not react with Mouse. Others-not known.

Please select from the items below to add to your shopping cart:

	Cat. # MS-1326 - P0
	( 0.1ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-1326 - P1
	( 0.5ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-1326 - P
	( 1.0ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-1326 - P1ABX
	( 0.1ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-1326 - PABX
	( 0.2ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-1326 - PCL
	( 0.1ml at 250ug/0.1ml) ( Positive Control for Western Blot)