Mcl-1 Ab-1

Antibodies

Mcl-1 Ab-1

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Compare different antibodies against Mcl-1.

Mouse Monoclonal Antibody*

Description: Mcl-1 (Myeloid cell leukemia-1) is a member of the bcl-2 family. The carboxy terminal of Mcl-1 and bcl-2 share significant sequence homology. Expression of Mcl-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g. ionizing radiation, ultraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in bcl-2. Enhanced expression of Mcl-1, prominently associated with mitochondria, complements the continued expression of bcl-2 in ML-1 cells undergoing differentiation. Like bcl-2, Mcl-1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis.

IgIsotype: IgG1 / kappa

Epitope: aa 1-327

Clone Designation: RC13

Immunogen: Recombinant human Mcl-1 protein corresponding to aa 1-327.

Positive Control:Raji cells.

Cellular Localization:Predominantly nuclear; occasionally cytoplasmic.

Molecular Weight:42kDa

Species reactivity:Human. Others-not known.

Please select from the items below to add to your shopping cart:

	Cat. # MS-681 - P0
	( 0.1ml at 400ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-681 - PABX
	( 0.2ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-681 - P1ABX
	( 0.1ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-681 - P
	( 1.0ml at 400ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-681 - PCL
	( 0.1ml at 250ug/0.1ml) ( Positive Control for Western Blot)
	Cat. # MS-681 - B0
	( 0.1ml at 400ug/ml) ( Biotin labeled Ab with BSA and Azide)
	Cat. # MS-681 - P1
	( 0.5ml at 400ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-681 - B1
	( 0.5ml at 400ug/ml) ( Biotin labeled Ab with BSA and Azide)
	Cat. # MS-681 - B
	( 1.0ml at 400ug/ml) ( Biotin labeled Ab with BSA and Azide)