Ku (p70) Ab-4

Antibodies

Ku (p70) Ab-4

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Click here to view PCL datasheet

Compare different antibodies against Ku.

Mouse Monoclonal Antibody

Description: The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

IgIsotype: IgG2b

Epitope: aa 506-541

Clone Designation: N3H10

Immunogen: Human placental extract designated as PSE1-PL

Positive Control:BT474, T47D, HEP-G-2 or HeLa cells. Tonsil

Cellular Localization:Nuclear

Molecular Weight:70kDa

Species reactivity:Human, Monkey, and Xenopus. Mouse & Hamster (Western blotting only). Does not react with cow, rabbit, and sea urchin.

Please select from the items below to add to your shopping cart:

	Cat. # MS-329 - P1ABX
	( 0.1ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-329 - PCL
	( 0.1ml at 250ug/0.1ml) ( Positive Control for Western Blot)
	Cat. # MS-329 - P0
	( 0.1ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-329 - P1
	( 0.5ml at 200ug/ml) ( Purified Ab with BSA and Azide)
	Cat. # MS-329 - PABX
	( 0.2ml at 1.0mg/ml) ( Purified Ab without BSA and Azide)
	Cat. # MS-329 - R7
	( 7.0ml ) ( Ready-to-use for Immunohistochemical Staining)
	Cat. # MS-329 - PCS
	( Positive Control for Histology, a set of 5 slides)
	Cat. # MS-329 - P
	( 1.0ml at 200ug/ml) ( Purified Ab with BSA and Azide)

Formalin-fixed, paraffin-embedded human tonsil stained with NeoMarkers' Ku Ab-4 (Cat. #MS-329-P) using peroxidase-conjugate and AEC chromogen. Note nuclear staining of epithelial cells and lymphocytes.