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S100 Protein Ab-1
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Compare different antibodies against S100 Protein.
Mouse Monoclonal Antibody
Description: S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.
Comments: Antibody to S100 stains Schwannomas, ependymomas, astrogliomas, almost all benign and malignant melanomas and their metastases. Ab-1 is excellent for immuno-histochemical staining of formalin-fixed, paraffin-embedded tissues. S100 protein is highly solouble and may be eluted from frozen tissue during staining.
IgIsotype: IgG2a
Epitope: Not determined
Clone Designation: 4C4.9
Immunogen: Purified bovine brain S100 protein
Positive Control:Melanoma or Schwannoma
Cellular Localization:Cytoplasmic
Molecular Weight:~22kDa (non-reduced); ~11kDa (reduced)
Species reactivity:Human, Cow, Rat, and Mouse. Others-not known.
  
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