Rabbit Monoclonal Antibodies

NEWS

Comprehensive Breast Panel available now. Higher sensitivity and specificity to accurately assess your patient.
View our Breast Panel

Read more....

Estrogen Receptor SP1 (RM-9101) receives FDA 510(k) approval.
Read more....


PTMTM : an integrated solution for any Autostainer for dewaxing and HIER


Literature

 Tutorial Center



   Search:      Account Login   View Shopping Cart

Antibodies

Alphabetical List of Antibodies

Click on letters below to search for antibodies:



To search for antibodies by research interest click here.

To search for New 2010 antibodies click here.

 

 

FEATURED ANTIBODY:
c-erbB-2 / HER-2 / neu..

 

Click here to view datasheet Click here to view datasheet

Rabbit Monoclonal Antibody

Description: HER2 gene encodes a transmembrane glycoprotein with tyrosine kinase activity. It is closely related in structure to the epidermal growth factor receptor c-erbB-3/HER3/neu oncoprotein. The protein is detectable in a subset of breast and other carcinomas (urinary bladder, stomach, lung, endometrium and ovary). In the case of breast cancer, over expression determined by immunohistochemistry has been shown to be associated with poor prognosis and an indication to initiate trastuzumab/herceptin therapy.

Epitope: not determined

Clone Designation: EP1045Y

Immunogen: A synthetic peptide corresponding to the c-terminus of human Her2

Positive Control:Breast carcinomas

Molecular Weight:185kDa

Species reactivity:Human. Others not tested.

Cellular Localization:Cell membrane


Formalin-fixed, paraffin-embedded breast carcinoma stained with rabbit monoclonal anti-HER-2 antibody (cat. #RM-2112-S) using peroxidase conjugate and DAB chromogen. Note membrane staining of tumor cells.



Copyright © 2010 Thermo Fisher Scientific Inc. and its subsidiaries. All rights reserved.
Thermo Fisher Scientific Inc.
4481 Campus Drive, Kalamazoo, MI 49008
 Main: 269-544-5600 / 800-522-7670 option1, Fax: 269-372-2674 / 877-815-2608
Email: labvision@thermo.com
The company doesn't accept credit card information via fax or email. Please contact customer service to process credit card orders.




Part of Thermo Fisher Scientific

 Featured New Products
c-erbB-2 / HER-2 / neu..
Rabbit Monoclonal Antibody

more info


 Featured Product
Multivision Detection System
Superiority in Double Staining


Come Visit Us!


Pathology Corner